Which anticoagulant is associated with inhibiting prothrombin conversion?

Which anticoagulant is associated with inhibiting prothrombin conversion?

• A. Sodium Fluoride
• B. EDTA
• C. Lithium Heparin
• D. Potassium oxalate

Answer: (C)

The correct response is associated with lithium heparin, which is a direct inhibitor of thrombin and plays a pivotal role in the coagulation cascade. Its primary function is to prevent the conversion of prothrombin to thrombin, which is a critical step in blood coagulation. This inhibition helps maintain the sample in a liquid state and is particularly beneficial for various laboratory tests that require plasma. Additionally, the other anticoagulants serve different purposes. Sodium fluoride, for instance, is primarily used to preserve glucose samples and does not specifically inhibit prothrombin conversion. EDTA works by binding calcium ions, which are essential for the coagulation process, but it does not directly inhibit thrombin. Potassium oxalate also acts primarily by binding calcium, similar to EDTA, rather than directly affecting prothrombin conversion.

The correct response is associated with lithium heparin, which is a direct inhibitor of thrombin and plays a pivotal role in the coagulation cascade. Its primary function is to prevent the conversion of prothrombin to thrombin, which is a critical step in blood coagulation. This inhibition helps maintain the sample in a liquid state and is particularly beneficial for various laboratory tests that require plasma.

Additionally, the other anticoagulants serve different purposes. Sodium fluoride, for instance, is primarily used to preserve glucose samples and does not specifically inhibit prothrombin conversion. EDTA works by binding calcium ions, which are essential for the coagulation process, but it does not directly inhibit thrombin. Potassium oxalate also acts primarily by binding calcium, similar to EDTA, rather than directly affecting prothrombin conversion.